Carboxytherapy or treatment with carbon dioxide is a relatively new method of treatment, which is now widely spread as a procedure to help patients with migraines, diseases of joints and other diagnoses, accompanied by pain. Carboxytherapy in Plissa health resort is injections of micro-doses of CO2 into the patient’s body to activate its reserve forces. The technique is about that the body perceives increase in CO2 content as hypoxia or nutrient deficiency, which triggers biochemical processes of metabolism normalisation and leads to pain relief